Biological Activitypep4c is an inactive control peptide analog of pep2m, a peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF).
Active Analog also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Role of AMPA receptor cycling in synaptic transmission and plasticity.
L?scher et al.
NSF binding to GluR2 regulates synaptic transmission.
Nishimune et al.
Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism.
Noel et al.
Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction.
Luthi et al.
Functional roles of protein interactions with AMPA and kainate receptors.
Collingridge and Isaac
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VersaClone cDNA Plasmids
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