Catalog Number: 1596
Alternate Names: GluR4cr
Biological Activity
Inactive control peptide analog of pep2m, a peptide inhibitor of the interaction between the C-terminus of the GluR2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF).

Active Analog also available.

Technical Data
  • M.Wt:
    1146.42
  • Formula:
    C48H91N17O13S
  • Sequence:
    KRMKVAKSAQ
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    243843-43-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Role of AMPA receptor cycling in synaptic transmission and plasticity.
    L?scher et al.
    Neuron, 1999;24:649
  2. Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism.
    Noel et al.
    Neuron, 1999;23:365
  3. NSF binding to GluR2 regulates synaptic transmission.
    Nishimune et al.
    Neuron, 1998;21:87
  4. Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction.
    Luthi et al.
    Neuron, 1999;24:389
  5. Functional roles of protein interactions with AMPA and kainate receptors.
    Collingridge and Isaac
    Neurosci.Res., 2003;47:3
Tocris Peptides
Description Application Cat# Citations Images  

pep2m

1595 1  
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