Chemical Name: 2-(2,2-Dicyclohexylethyl)piperidine maleate
Biological ActivityPerhexiline maleate is a carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor. Inhibits palmitate oxidation in rat cardiomyocytes and increases cardiac efficiency in isolated rat hearts. Antianginal.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Dissociation between metabolic and efficiency effects of perhexiline in normoxic rat myocardium.
Unger et al.
Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome.
Yin et al.
Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiod.
Kennedy et al.
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