Potent and selective hM3
DREADD agonist (EC50
= 2.8 nM). Exhibits >10,000-fold selectivity for hM3
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All Tocris products are intended for laboratory research use only.
The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs.
Chen et al.
ACS Chem.Neurosci., 2015;18:476