PF 04628935

Tocris Bioscience | Catalog # 6347

Potent ghrelin receptor inverse agonist
Tocris Bioscience

Key Product Details

Description

Potent ghrelin receptor inverse agonist
View all Ghrelin Receptor Inverse Agonists »

Product Description

PF 04628935 is a potent ghrelin receptor inverse agonist (IC50 = 4.6 nM). Orally bioavailable and exhibits reasonable brain penetration.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for PF 04628935

Molecular Weight

496.03

Formula

C24H26ClN7OS

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

1-[2-[[2-Chloro-4-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone

CAS Number

1383719-97-8

PubChem ID

70682037

InChI Key

MTDYDDJVCIHZKH-UHFFFAOYSA-N

SMILES

ClC1=C(CN2CC3(CCN(C(CC4=CN(C=C(C)S5)C5=N4)=O)CC3)C2)C=CC(N6N=CC=N6)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 24.8 50
Ethanol 9.92 20

Preparing Stock Solutions for PF 04628935

The following data is based on the product molecular weight 496.03.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.03 mL 20.16 mL 40.32 mL
2.5 mM 0.81 mL 4.03 mL 8.06 mL
5 mM 0.40 mL 2.02 mL 4.03 mL
25 mM 0.08 mL 0.40 mL 0.81 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for PF 04628935

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PF 04628935

For research use only

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