PF 750

Catalog # Availability Size / Price Qty
3307/10
3307/50
PF 750 | CAS No. 959151-50-9 | Fatty Acid Amide Hydrolase (FAAH) Inhibitors
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Description: Selective FAAH inhibitor

Chemical Name: N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide

Purity: ≥98%

Product Details
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Biological Activity

Irreversible fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active.

Technical Data

M.Wt:
345.44
Formula:
C22H23N3O
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at RT
CAS No:
959151-50-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.
    Ahn et al.
    Biochemistry, 2007;46:13019
  2. Structure-guided inhibitor design for human FAAH by interspecies active site conversion.
    Mileni et al.
    Proc.Natl.Acad.Sci.USA, 2008;105:12820

Product Datasheets

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