Chemical Name: (5Z)-5-[(4-Hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone
Biological ActivityPFM 01 is a MRE11 endonuclease inhibitor. Prevents double-stranded break (DSB) resection. Enhances non-homologous end-joining (NHEJ) and reduces homologous recombination.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities.
Shibata et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for PFM 01
There are currently no reviews for this product. Be the first to review PFM 01 and earn rewards!
Have you used PFM 01?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image