PG 931
Tocris Bioscience | Catalog # 5094
Potent and selective MC4 receptor agonist
Discontinued Product
5094 has been discontinued.
View all Melanocortin Receptor Agonists products.
Key Product Details
Description
Potent and selective MC4 receptor agonist
Product Description
PG 931 is a potent and selective melanocortin 4 (MC4) receptor agonist (IC50 values are 0.58 and 55 nM for human MC4 and MC3 receptors respectively). Produces a rapid and dose dependent restoration of cardiovascular and respiratory function in hemorrhage-shocked rats.
Product Specifications for PG 931
Molecular Weight
1180.41
Formula
C59H85N15O11
Storage
Store at -20°C
CAS Number
667430-81-1
PubChem ID
90489007
InChI Key
WOFDJLFPEWSAPJ-RVBGBMFGSA-N
SMILES
CCCCC(NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H]2CCCN2C1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 2mg/ml in 25% ethanol / water |
Calculators
Background References
References are publications that support the biological activity of the product.
- Grieco Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. J.Pept.Res. 2003 PMID: 14531843
- Giuliani Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage. Br.J.Pharmacol. 2007 PMID: 17245369
Product Documents for PG 931
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for PG 931
For research use only
Related Research Areas
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