[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
Tocris Bioscience | Catalog # 3229
Selective B2 agonist
Discontinued Product
3229 has been discontinued.
View all Bradykinin Receptor Agonists products.
Product Description
[Phe8Ψ(CH-NH)-Arg9]-Bradykinin is a selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin (Cat No. 3004) in vivo.
Product Specifications for [Phe8Ψ(CH-NH)-Arg9]-Bradykinin
Molecular Weight
1046.23
Formula
C50H75N15O10
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
118122-39-7
PubChem ID
3082903
InChI Key
XKJBISGEHGXKBF-TZPCGENMSA-N
SMILES
[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@H](CN[C@@H](CCCNC(N)=N)C(O)=O)CC1=CC=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product.
- Marceau Kinin receptors: functional aspects. Int.Immunopharmacol. 2002 PMID: 12489786
- Leeb-Lundberg International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 2005 PMID: 15734727
- Drapeau [Phe8Ψ(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II. Eur.J.Pharmacol. 1988 PMID: 2907489
Product Documents for [Phe8Ψ(CH-NH)-Arg9]-Bradykinin
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for [Phe8Ψ(CH-NH)-Arg9]-Bradykinin
For research use only
Citations for [Phe8Ψ(CH-NH)-Arg9]-Bradykinin
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Species: RatAssay Type: In VitroCell Line/Tissue: neuronsVerified Customer | Posted 05/13/202020 nM bradykinin
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