Catalog Number: 3229
Biological Activity
Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin (Cat No. 3004) in vivo.
Technical Data
  • M.Wt:
    1046.23
  • Formula:
    C50H75N15O10
  • Sequence:
    RPPGFSPFR

    (Modifications: Phe-8 - Arg-9 peptide bond replaced with Ψ-(CH2-NH))

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    118122-39-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. [Phe8Ψ(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II.
    Drapeau et al.
    Eur.J.Pharmacol., 1988;155:193
  2. Kinin receptors: functional aspects.
    Marceau et al.
    Int.Immunopharmacol., 2002;2:1729
  3. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences.
    Leeb-Lundberg et al.
    Pharmacol.Rev., 2005;57:27

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