Biological ActivitySelective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin (Cat No. 3004) in vivo.
(Modifications: Phe-8 - Arg-9 peptide bond replaced with Ψ-(CH2-NH))
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences.
Leeb-Lundberg et al.
[Phe8Ψ(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II.
Drapeau et al.
Kinin receptors: functional aspects.
Marceau et al.
Citation for [Phe8Ψ(CH-NH)-Arg9]-Bradykinin
The citations listed below are publications that use Tocris products. Selected citations for [Phe8Ψ(CH-NH)-Arg9]-Bradykinin include:
1 Citation: Showing 1 - 1
Modulation of cardiac vagal tone by bradykinin acting on nucleus ambiguus.
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