Biological Activity[Phe8Ψ(CH-NH)-Arg9]-Bradykinin is a selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin (Cat No. 3004) in vivo.
(Modifications: Phe-8 - Arg-9 peptide bond replaced with Ψ-(CH2-NH))
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Tocris products are intended for laboratory research use only, unless stated otherwise.
International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences.
Leeb-Lundberg et al.
[Phe8Ψ(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II.
Drapeau et al.
Kinin receptors: functional aspects.
Marceau et al.
Citation for [Phe8Ψ(CH-NH)-Arg9]-Bradykinin
The citations listed below are publications that use Tocris products. Selected citations for [Phe8Ψ(CH-NH)-Arg9]-Bradykinin include:
1 Citation: Showing 1 - 1
Modulation of cardiac vagal tone by bradykinin acting on nucleus ambiguus.
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