Phentolamine Mesylate

Tocris Bioscience | Catalog # 6431

Adrenergic α receptor antagonist; antihypertensive
Tocris Bioscience

Key Product Details

Description

Adrenergic α receptor antagonist; antihypertensive
View all Adrenergic alpha-1 Receptor Antagonists »

Product Description

Phentolamine Mesylate is a non-selective adrenergic α receptor antagonist (pKB = 8.07). Intravenous injection causes hypotension and tachycardia in rats. Intraperitoneal injection in mice increases plasma FGF21 levels.

Product Specifications for Phentolamine Mesylate

Molecular Weight

377.46

Formula

C17H19N3O.CH4O3S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]phenol methanesulfonate

CAS Number

65-28-1

PubChem ID

91430

InChI Key

OGIYDFVHFQEFKQ-UHFFFAOYSA-N

SMILES

CS(O)(=O)=O.CC1=CC=C(N(C2=CC(O)=CC=C2)CC3=NCCN3)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 37.75 100
DMSO 37.75 100

Preparing Stock Solutions for Phentolamine Mesylate

The following data is based on the product molecular weight 377.46.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.65 mL 13.25 mL 26.49 mL
5 mM 0.53 mL 2.65 mL 5.30 mL
10 mM 0.26 mL 1.32 mL 2.65 mL
50 mM 0.05 mL 0.26 mL 0.53 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 10 publications citing the usage of this product.

Product Documents for Phentolamine Mesylate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Phentolamine Mesylate

For research use only

Citations for Phentolamine Mesylate

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