Phenyl-glutarimide 4'-oxyacetic acid

Catalog # Availability Size / Price Qty
Phenyl-glutarimide 4'-oxyacetic acid | CAS No. 2782024-58-0 | Degrader Building Blocks
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Description: Functionalized cereblon ligand for PROTAC development

Chemical Name: 2-(4-(2,6-Dioxopiperidin-3-yl)phenoxy)acetic acid

Purity: ≥95%

Product Details

Biological Activity

Phenyl-glutarimide 4'-oxyacetic acid is a carboxylic acid-functionalized cereblon ligand that can be used for PROTAC® Degrader development. The compound can be used to develop PG-PROTACs that exhibit improved stability to hydrolysis and potency compared with PROTACs synthesized using IMiD (immunomodulatory imide drug) analogs

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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