Phospho-TAO2 (S181) Antibody

• Species Reactivity
  Human, Mouse, Rat, Xenopus
• Specificity
  This antibody is specific for the ~120 kDa TAO2 phosphorylated at S181 in Western blots of rat cortex lysate.
• Source
  Polyclonal Rabbit IgG
• Purification
  Antigen Affinity-purified
• Immunogen
  Phosphopeptide corresponding to amino acid residues surrounding the phospho-S181 of TAO2
• Formulation
  100 μL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.
• Label
  Unconjugated

• Western Blot
  1:1000 dilution
  See below

Western Blot click image to view larger

Detection of Phospho-TAO2 (S181) by Western Blot. Western blot of rat cortex lysate showing specific immunolabeling of the ~120 kDa TAO2 phosphorylated at S181 (Control). The phosphospecificity of this labeling is demonstrated by treatment with 1200 units of lambda phosphatase ( lambda PPase) for 30 minutes before being exposed to the anti-Phospho-TAO2 (S181). The immunolabeling is completely eliminated by treatment with lambda PPase.

• Shipping
  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
• Stability & Storage
  For long-term storage, ≤ ‑20° C is recommended. Product is stable at ≤ ‑20° C for at least 1 year.

• References:
  1. Chen, Z. et al. (1999) J. Biol. Chem. 274:28803.
  2. Chen, Z. and M.H. Cobb (2001) J. Biol. Chem. 276:16070.
  3. Moore, T.M. et al. (2000) J. Biol. Chem. 275:4311.
  4. Zhou, T. et al. (2004) Structure 12:1891.
  5. SwissProt Accession #: Q9UL54.

• Long Name:
  Serine/Threonine-protein Kinase TAO2

• Entrez Gene IDs:
  9344 (Human); 381921 (Mouse); 64666 (Rat)

• Alternate Names:
  EC 2.7.11; KFC-C; KIAA0881PSK-1; Kinase from chicken homolog C; MAP3K17; MAP3K17PSK1-BETA; Prostate-derived STE20-like kinase 1; PSK1; PSK1EC 2.7.11.1; PSKhKFC-C; serine/threonine-protein kinase TAO2; TAO kinase 2; TAO1; TAO2; TAO2prostate derived STE20-like kinase PSK; TAOK2; Thousand and one amino acid protein 2; thousand and one amino acid protein kinase

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