Catalog Number: 0694
Chemical Name: (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride
Biological Activity
Muscarinic agonist.
Technical Data
  • M.Wt:
    244.72
  • Formula:
    C11H16N2O2.HCl
  • Solubility:
    Soluble to 75 mM in DMSO and to 100 mM in water
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
  • CAS No:
    54-71-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current.
    Wang et al.
    Br.J.Pharmacol., 1999;126:1725
  2. Differences in the prejunctional effects of methacholine and pilocarpine on the release of endogenous acetylcholine from guinea-pig trachea.
    ten Berge et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1996;354:606
  3. Muscarinic receptor agonists and antagonists.
    Brown and Taylor
    The Pharmacological Basis of Therapeutics. Eds Goo, 1996;:Chapter 7, p147
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Pilocarpine hydrochloride include:

2 Citations: Showing 1 - 2
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  1. The structure of the trabecular meshwork, its connections to the ciliary muscle, and the effect of pilocarpine on outflow facility in mice.
    Authors: Overby Et al.
    Nat Chem Biol 2014;55:3727
  2. Glutamate carboxypeptidase II (GCPII) inhibitor displays anti-glutamate and anti-cocaine effects in an invertebrate assay.
    Authors: Tallarida Et al.
    Amino Acids 2012;42:2521

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