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PIM-1 Inhibitor 2

3589 1 Citation Datasheet / COA / SDS
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3589/50
3589/10
PIM-1 Inhibitor 2 | CAS No. 477845-12-8 | Pim Kinase Inhibitors
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Description: Pim-1 kinase inhibitor

Chemical Name: 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Potent Pim-1 kinase inhibitor (Ki = 91 nM).

Technical Data

M.Wt:
322.75
Formula:
C17H11ClN4O
Solubility:
Soluble to 75 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
477845-12-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase.
    Pierce et al.
    J.Med.Chem., 2008;51:1972

Product Datasheets

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Citation for PIM-1 Inhibitor 2

The citations listed below are publications that use Tocris products. Selected citations for PIM-1 Inhibitor 2 include:

1 Citation: Showing 1 - 1

  1. Inhibition of the Pim1 oncogene results in diminished visual function.
    Authors: Yin Et al.
    PLoS One  2013;7:e52177

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