Pirenzepine dihydrochloride

Key Product Details

Product Description

Pirenzepine dihydrochloride is a M₁ muscarinic receptor selective antagonist. Inverse agonist activity reported.

Product Specifications for Pirenzepine dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Pirenzepine dihydrochloride

The following data is based on the product molecular weight 424.33.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

6 5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.36 mL	11.78 mL	23.57 mL
5 mM	0.47 mL	2.36 mL	4.71 mL
10 mM	0.24 mL	1.18 mL	2.36 mL
50 mM	0.05 mL	0.24 mL	0.47 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 36 publications citing the usage of this product.

• Hammer Pirenzepine distinguishes between different subclasses of muscarinic receptors. Nature 1980 PMID: 7350532
• Doods Pharmacological profile of selective muscarinic receptor antagonists on guinea-pig ileal smooth muscle. Eur.J.Pharmacol. 1994 PMID: 8200421
• Eglen Muscarinic receptor subtypes and smooth muscle function. Pharmacol.Rev. 1996 PMID: 8981565
• Daeffler Inverse agonist activity of pirenzepine at M₂ muscarinic acetylcholine receptors. Br.J.Pharmacol. 1999 PMID: 10205015

Product Documents for Pirenzepine dihydrochloride