Pitavastatin calcium

Catalog # Availability Size / Price Qty
4942/10
4942/50
Cat.No. 4942 - Pitavastatin calcium | C25H23FNO4.0.5Ca | CAS No. 147526-32-7
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Description: HMG-CoA reductase inhibitor
Alternative Names: NK-104

Chemical Name: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid hemicalcium salt

Purity: ≥99%

Product Details
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Biological Activity

Synthetic inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Lowers low-density lipoprotein (LDL) cholesterol levels. Displays minimal metabolism by cytochrome P450 enzymes, with little involvement of CYP3A4. Shown to improve cardiac function and survival in a rat model of hypertensive heart failure.

Technical Data

M.Wt:
440.5
Formula:
C25H23FNO4.0.5Ca
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
147526-32-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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