PK 11195

Catalog # Availability Size / Price Qty
0670/10
0670/50
Cat.No. 0670 - PK 11195 | C21H21ClN2O | CAS No. 85532-75-8
1 Image
Description: Antagonist at peripheral benzodiazepine receptors

Chemical Name: 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide

Purity: ≥98%

Product Details
Citations (3)
Reviews (1)

Biological Activity

Possesses high affinity for the peripheral benzodiazepine receptor (PBR, TSPO) without binding to other known neurotransmitter receptors. Also inhibits the human constitutive androstane receptor (hCAR).

Technical Data

M.Wt:
352.86
Formula:
C21H21ClN2O
Solubility:
Soluble to 50 mM in ethanol and to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
85532-75-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for PK 11195

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for PK 11195

Average Rating: 5 (Based on 1 Review)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used PK 11195?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


A peripheral benzodiazepine receptor (PBR) agonist.
By Anonymous on 05/02/2018
Species: Human

It is a peripheral benzodiazepine receptor (PBR) agonist. It is effective in inhibiting LPS-induced pro-inflammatory cytokines such as IL-1beta and TNF-alpha in microglia culture.


Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.