PK 11195

  ( 3 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:0670
Chemical Name:1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
Product Details
Citations (3)
Reviews
Biological Activity
Possesses high affinity for the peripheral benzodiazepine receptor (PBR, TSPO) without binding to other known neurotransmitter receptors. Also inhibits the human constitutive androstane receptor (hCAR).
Technical Data
  • M.Wt:
    352.86
  • Formula:
    C21H21ClN2O
  • Solubility:
    Soluble to 50 mM in ethanol and to 50 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    85532-75-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for PK 11195 include:

3 Citations: Showing 1 - 3
Filter your results:

  1. Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.
    Authors: Gut Et al.
    J Cell Mol Med  2013;9:97
  2. Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR).
    Authors: Anderson Et al.
    Toxicol Lett  2011;202:148
  3. Ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in oesophageal cancer cells: involvement of the p38MAPK signalling pathway.
    Authors: Sutter Et al.
    Nat Chem Biol  2003;89:564

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs
Average Rating: 5 (Based on 1 review)

Have you used PK 11195?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Read what people are saying who have used PK 11195.

We have 1 review tested in 1 species: Human.

Filter by Ratings
Excellent
(1)
All Ratings
Filter by Applications
All Applications
Filter by Species
Human
(1)
All Species

Images Ratings Applications Species Reviewed By Date Details
  Excellent
  Human Anonymous 05/02/2018
Show

Summary

Species Human

Please scroll the above reviews for more
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee