PKC β pseudosubstrate

   
Product Datasheet
Catalog Number:1792
Alternate Names:Protein kinase C beta pseudosubstrate
Chemical Name:
Product Details
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Biological Activity
Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM). Consists of amino acids 19 - 31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide.
Technical Data
  • M.Wt:
    3994.84
  • Formula:
    C177H294N62O38S3
  • Sequence:
    CRQIKIWFQNRRMKWKK CRFARKGALRQKNV*

    (Modifications: Disulfide bridge between 17 -1*)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    172308-76-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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