PKC β pseudosubstrate

Catalog # Availability Size / Price Qty
1792/1
PKC β pseudosubstrate
1 Image
Description: Selective cell-permeable PKC inhibitor peptide (attached to vector)
Alternative Names: Protein kinase C beta pseudosubstrate
Product Details
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Biological Activity

Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM). Consists of amino acids 19 - 31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide.

Technical Data

M.Wt:
3994.84
Formula:
C177H294N62O38S3
Sequence:
CRQIKIWFQNRRMKWKK CRFARKGALRQKNV*

(Modifications: Disulfide bridge between 17 -1*)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
172308-76-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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