Cell-permeable version of protein kinase inhibitor PKI (14-22) amide. The non-myristoylated version inhibits protein kinase A (Ki
= 36 nM), inhibits cell growth and induces apoptosis in human pancreatic cancer cells (PANC-1).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitory protein.
Glass et al.
Activation of apolipoprotein AI gene expression by protein kinase A and kinase C through transcription factor, Sp1.
Zheng et al.
Inhibition of pancreatic cancer cell growth and induction of apoptosis with novel therapies directed against protein kinase A.
Farrow et al.
The citations listed below are publications that use Tocris products. Selected citations for PKI 14-22 amide, myristoylated include:
Showing Results 1 - 9 of 9