PKI 14-22 amide, myristoylated

Tocris Bioscience | Catalog # 2546

Cell-permeable protein kinase A inhibitor
Tocris Bioscience

Key Product Details

Description

Cell-permeable protein kinase A inhibitor

Alternative Names

Protein kinase inhibitor-(14-22)-amide,myristoylated
View all Protein Kinase A Inhibitors »

Product Description

PKI 14-22 amide, myristoylated is a cell-permeable version of protein kinase inhibitor PKI (14-22) amide. The non-myristoylated version inhibits protein kinase A (Ki = 36 nM), inhibits cell growth and induces apoptosis in human pancreatic cancer cells (PANC-1).

Product Specifications for PKI 14-22 amide, myristoylated

Molecular Weight

1209.50

Formula

C53H100N20O12

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

201422-03-9

PubChem ID

71312213

InChI Key

GQPQKQWUUHDDIS-JDLJUXOTSA-N

SMILES

[H]N(CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(N)=O)C(=O)CCCCCCCCCCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in DMSO

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Product Documents for PKI 14-22 amide, myristoylated

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PKI 14-22 amide, myristoylated

For research use only

Citations for PKI 14-22 amide, myristoylated

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  • Cyclic AMP Pathway-related studies
    Name: MARINA KOUTSIOUMPA
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 10/13/2022
    PKI 14-22 amide, myristoylated was used in studies exploring the role of PKA in mediating drug-induced activation of the cyclic AMP pathway.

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