Catalog Number: 6221
Biological Activity
High affinity PKA inhibitor (Ki = 2.3 nM).
Technical Data
  • M.Wt:
    2222.4
  • Formula:
    C94H148N32O31
  • Sequence:
    TTYADFIASGRTGRRNAIHD
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    99534-03-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase.
    Cheng et al.
    J.Biol.Chem., 1986;261:989
  2. Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.
    Narayana et al.
    Biochemistry, 1997;36:4438
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