PLGRKT Recombinant Protein Antigen

Novus Biologicals | Catalog # NBP1-89254PEP

Novus Biologicals
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Key Product Details

Source

E. coli

Applications

Antibody Competition
View all PLGRKT Proteins and Enzymes »

Product Specifications

Description

A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human PLGRKT.

Source: E. coli

Amino Acid Sequence: QKEFMLMNARLQLERQLIMQSEMRERQMAMQIAWSRE

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Antibody Competition (10 - 100 molar excess)

Application Notes

This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-89254.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Protein / Peptide Type

Recombinant Protein Antigen

Formulation, Preparation, and Storage

NBP1-89254PEP
Formulation PBS and 1M Urea, pH 7.4.
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: PLGRKT

Plasminogen is the precursor of plasmin, an active serine protease that dissolves the fibrin of blood clots and acts in many other processes such as embryonic development, tissue remodeling, inflammation and tumor invasion. Synthesized in the kidney, plasminogen is found in plasma and many extracellular fluids. Activated by u- or t-plasminogen activator, the single-chain plasminogen is converted to plasmin that consists of a disulfide bond-linked heavy chain A and light chain B. Heavy chain A contains 5 kringle domains and light chain B corresponds to the serine protease domain. A fragment consisting of the first 4 kringle domains has been named angiostatin, a novel angiogenesis inhibitor.

Long Name

Plasminogen Receptor (KT)

Alternate Names

C9orf46, MDS030, PLG-RKT

Gene Symbol

PLGRKT

Additional PLGRKT Products

Product Documents for PLGRKT Recombinant Protein Antigen

Certificate of Analysis

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Product Specific Notices for PLGRKT Recombinant Protein Antigen

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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