Catalog Number: 2567
Alternate Names: Proteolipid protein (139-151)
Biological Activity
Synthetic myelin proteolipid protein (PLP) fragment. Immunization with this peptide induces severe clinical and histological experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:
  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein.
    Sobel et al.
    J.Neuropathol.Exp.Neurol., 1990;49:468
  2. Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides.
    Kuchroo et al.
    Pathobiology., 1991;59:305
  3. Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice.
    Tuohy et al.
    J.Immunol., 1989;142:1523
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