PLP (139-151)

Name: PLP (139-151)
Brand: Tocris Bioscience
SKU: 2567
Price: 177 USD
Availability: InStock

Tocris Bioscience | Catalog # 2567

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Citations (2)

Product Documents

Encephalitogenic myelin proteolipid fragment

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Encephalitogenic myelin proteolipid fragment

Alternative Names

Proteolipid protein (139-151)

View all Neuronal Metabolism Peptides and Compounds »

Product Description

PLP (139-151) is a synthetic myelin proteolipid protein (PLP) fragment. Immunization with this peptide induces severe clinical and histological experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis.

Product Specifications for PLP (139-151)

Molecular Weight

1521.74

Formula

C₇₂H₁₀₄N₂₀O₁₇

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

122018-58-0

PubChem ID

16199055

InChI Key

UQIBUOXNUPHALR-UVIWMAFZSA-N

SMILES

[H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 2mg/ml in water

Calculators

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Mass

Concentration

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g/mol

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Background References

References are publications that support the biological activity of the product.

Sobel Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. J.Neuropathol.Exp.Neurol. 1990 PMID: 2273404
Kuchroo Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology. 1991 PMID: 1716908
Tuohy Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. J.Immunol. 1989 PMID: 2465343

Product Documents for PLP (139-151)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for PLP (139-151)

For research use only

Citations for PLP (139-151)

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