PLpro inhibitor 19
Chemical Name: (R)-N-(3-Fluoro-5-((1-(1-(naphthalen-1-yl)ethyl)piperidine-4-carboxamido)methyl)phenyl)-4-methylpiperazine-1-carboxamide
Biological ActivityPLpro inhibitor 19 is a SARS-CoV-2 inhibitor that inhibits viral replication and PLpro enzymatic activity in vitro (IC50 values are 0.18 μM and 0.44 μM respectively). PLpro inhibitor 19 is selective for PLpro over human deubiquitinating enzymes (DUBs) and DUB-like proteases and displays no cytotoxicity at up to 10 μM.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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