PLS1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-30592

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all PLS1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: DLIDAIAPNAVRQEMIRRENLSDEDKL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PLS1 Antibody - BSA Free

Immunohistochemistry-Paraffin: PLS1 Antibody [NBP2-30592]

Immunohistochemistry-Paraffin: PLS1 Antibody [NBP2-30592]

Immunohistochemistry-Paraffin: PLS1 Antibody [NBP2-30592] - Staining of human small intestine shows high expression.
Immunohistochemistry-Paraffin: PLS1 Antibody [NBP2-30592]

Immunohistochemistry-Paraffin: PLS1 Antibody [NBP2-30592]

Immunohistochemistry-Paraffin: PLS1 Antibody [NBP2-30592] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: PLS1 Antibody [NBP2-30592]

Immunohistochemistry-Paraffin: PLS1 Antibody [NBP2-30592]

Immunohistochemistry-Paraffin: PLS1 Antibody [NBP2-30592] - Staining in human small intestine and liver tissues using anti-PLS1 antibody. Corresponding PLS1 RNA-seq data are presented for the same tissues.

Applications for PLS1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PLS1

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. Fimbrin is a 68-kD actin-bundling protein. [provided by RefSeq]

Alternate Names

fimbrin, I plastin, intestine specific plastin, Intestine-specific plastin, I-plastin, plastin 1, plastin 1 (I isoform), Plastin-1

Gene Symbol

PLS1

UniProt

Q14651 (Human)

Additional PLS1 Products

Product Documents for PLS1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for PLS1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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