Recombinant Human PLUNC His Protein

Name: Recombinant Human PLUNC His Protein
Brand: Novus Biologicals
SKU: NBP2-22716
Price: 419 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-22716

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all PLUNC Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 20-256 of Human PLUNC

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSQFGGLPV PLDQTLPLNV NPALPLSPTG LAGSLTNALS NGLLSGGLLG ILENLPLLDI LKPGGGTSGG LLGGLLGKVT SVIPGLNNII DIKVTDPQLL ELGLVQSPDG HRLYVTIPLG IKLQVNTPLV GASLLRLAVK LDITAEILAV RDKQERIHLV LGDCTHSPGS LQISLLDGLG PLPIQGLLDS LTGILNKVLP ELVQGNVCPL VNEVLRGLDI TLVHDIVNML IHGLQFVIKV

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

27.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PLUNC His Protein

SDS-PAGE: Recombinant Human PLUNC His Protein [NBP2-22716]

SDS-Page: Recombinant Human PLUNC Protein [NBP2-22716]

Formulation, Preparation, and Storage

NBP2-22716

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.2 M NaCl, 30% glycerol
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PLUNC

BPIFA1, also known as PLUNC, belongs to the short subfamily of PLUNC family proteins and have homology only to the Nterminal domains of BPI. It is a secreted protein that is expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. BPIFA1 binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of BPIFA1 occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of BPIFA1 in the upper respiratory tract. Recombinant human BPIFA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Palate, Lung, and Nasal Epithelium Associated

Alternate Names

BPIFA1, LUNX, SPLUNC1

Gene Symbol

BPIFA1

Additional PLUNC Products

Product Documents for Recombinant Human PLUNC His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human PLUNC His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Host Defense/Innate Immunity

Inflammatory Mediators

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