(+)-SK&F 10047 hydrochloride

Name: (+)-SK&F 10047 hydrochloride
Brand: Tocris Bioscience
SKU: 1079
Price: 291 USD
Availability: InStock

Tocris Bioscience | Catalog # 1079

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Citations (7)

Product Documents

σ1 selective agonist

Product Description
Product Specifications
Solubility
Preparing Stock Solutions
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

σ1 selective agonist

View all Sigma1 Receptor Agonists »

Product Description

(+)-SK&F 10047 hydrochloride is a prototypical σ₁ receptor agonist. Behaviorally active in animal models of memory and stress.

Product Specifications for (+)-SK&F 10047 hydrochloride

Molecular Weight

293.84

Formula

C₁₇H₂₃NO.HCl

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

(2S,6S,11S)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol hydrochloride

CAS Number

133005-41-1

PubChem ID

16759596

InChI Key

ZTGMHFIGNYXMJV-XSCGHNKWSA-N

SMILES

Cl.C[C@@H]1[C@@H]2CC3=CC=C(O)C=C3[C@@]1(C)CCN2CC=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	29.38	100
	DMSO	29.38	100

Preparing Stock Solutions for (+)-SK&F 10047 hydrochloride

The following data is based on the product molecular weight 293.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.40 mL	17.02 mL	34.03 mL
5 mM	0.68 mL	3.40 mL	6.81 mL
10 mM	0.34 mL	1.70 mL	3.40 mL
50 mM	0.07 mL	0.34 mL	0.68 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.

Matsuno Involvement of σ₁ receptor in (+)-N-allylnormetazocine-stimulated hippocampal cholinergic functions in rats. Brain Res. 1995 PMID: 8535837
Walker Sigma receptors: biology and function. Pharmacol.Rev. 1990 PMID: 1964225
Kamei (+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress via DArgic systems linked to phenytoin-regulated σ₁ sites. Eur.J.Pharmacol. 1996 PMID: 8874133

Product Documents for (+)-SK&F 10047 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for (+)-SK&F 10047 hydrochloride

For research use only

Citations for (+)-SK&F 10047 hydrochloride

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