(+)-U-50488 hydrochloride

Tocris Bioscience | Catalog # 0471

Selective κ agonist; less active enantiomer of (±)-U-50488 (Cat. No. 0495)
Tocris Bioscience

Key Product Details

Description

Selective κ agonist; less active enantiomer of (±)-U-50488 (Cat. No. 0495)
View all Kappa Opioid Receptor Agonists »

Product Description

(+)-U-50488 hydrochloride is a less active enantiomer of (±)-U-50488.

Racemate and (-)-enantiomer also available.

Product Specifications for (+)-U-50488 hydrochloride

Molecular Weight

405.79

Formula

C19H26Cl2N2O.HCl

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride

CAS Number

114528-81-3

PubChem ID

6918162

InChI Key

KGMMGVIYOHGOKQ-JAXOOIEVSA-N

SMILES

O=C(CC3=CC(Cl)=C(Cl)C=C3)N([C@H]1[C@H](N2CCCC2)CCCC1)C.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 40.58 100
DMSO 40.58 100

Preparing Stock Solutions for (+)-U-50488 hydrochloride

The following data is based on the product molecular weight 405.79.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.46 mL 12.32 mL 24.64 mL
5 mM 0.49 mL 2.46 mL 4.93 mL
10 mM 0.25 mL 1.23 mL 2.46 mL
50 mM 0.05 mL 0.25 mL 0.49 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (+)-U-50488 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (+)-U-50488 hydrochloride

For research use only

Customer Reviews for (+)-U-50488 hydrochloride (1)

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  • Good product
    Name: Luca Zangrandi
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: CHO
    Verified Customer | Posted 03/05/2020
    Successfully induced ERK phosphorylation in CHO cells. Somehow weaker signal compared to other enantiomer.
    (+)-U-50488 hydrochloride 0471

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