PMPA (NAALADase inhibitor)

Catalog # Availability Size / Price Qty
1380/10
1380/50
Cat.No. 1380 - PMPA (NAALADase inhibitor) | C6H11O7P | CAS No. 173039-10-6
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Description: GCP II inhibitor

Chemical Name: 2-(Phosphonomethyl)pentane-1,5-dioic acid

Product Details
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Biological Activity

Highly potent and selective inhibitor of glutamate carboxypeptidase 2 (GCP II/N-acetylated α-linked dipeptidase/NAALADase) with a Ki value of 275 pM. Neuroprotective; protects against glutamate-mediated motor neuron degeneration and reduces volume of injury following middle cerebral artery occlusion (MCAO).

Technical Data

M.Wt:
226.12
Formula:
C6H11O7P
Solubility:
Soluble to 100 mM in water
Storage:
Desiccate at RT
CAS No:
173039-10-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold with the permission of AstraZeneca Ltd.

Product Datasheets

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