PNU 74654

  ( 5 citations )    
Product Datasheet
Catalog Number:3534
Chemical Name:2-Phenoxybenzoic acid-[(5-methyl-2-furanyl)methylene]hydrazide
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Binds to β-catenin (KD = 450 nM). Inhibits the interaction between β-catenin and T cell factor 4 (Tcf4) and disrupts the Wnt signaling pathway.
Technical Data
  • M.Wt:
    320.34
  • Formula:
    C19H16N2O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    113906-27-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for PNU 74654 include:

5 Citations: Showing 1 - 5
Filter your results:

  1. Transcription factor binding dynamics during human ES cell differentiation.
    Authors: Tsankov Et al.
    Stem Cells Int  2015;518:344
  2. Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.
    Authors: Liao Et al.
    Nature  2015;47:469
  3. Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem Cells to Cardiac Competent Progenitors.
    Authors: Yang Et al.
    Cell Reprogram  2015;2015:270428
  4. β-Cell differentiation of human pancreatic duct-derived cells after in vitro expansion.
    Authors: Corritore Et al.
    Ann Neurol  2014;16:456
  5. Genome-wide RNAi screen reveals a new role of a WNT/CTNNB1 signaling pathway as negative regulator of virus-induced innate immune responses.
    Authors: Baril Et al.
    PLoS Pathog  2013;9:e1003416

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used PNU 74654?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee