Pomalidomide 4'-PEG4-amine

Catalog # Availability Size / Price Qty
6963/25
Pomalidomide 4'-PEG4-amine | CAS No. 2357105-92-9 | Degrader Building Blocks
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Description: Cereblon ligand with PEG linker and terminal amine for onward chemistry
Alternative Names: Pomalidomide - linker 8

Chemical Name: 4-[(14-Amino-3,6,9,12-tetraoxatetradec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione hydrochloride

Purity: ≥95%

Product Details
Reviews (1)

Biological Activity

Functionalized cereblon ligand for PROTACsup>® research and development; incorporates an E3 ligase ligand plus a PEG4 linker with terminal ethylamine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Pomalidomide - linker 8

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage guidelines:

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
528.99
Formula:
C23H32N4O8.HCl
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2357105-92-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Key input for a Protac array targeting Cereblon E3
By Anonymous on 06/11/2020
Application: Species: Human

6963 was purchased along with additional PEGx linker's for an array of tool compounds to validate a bioluminescence assay


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