Porimin Antibody

Novus Biologicals | Catalog # NB100-56371

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Bovine

Cited:

Human, Mouse

Predicted:

Chicken (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin, Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all Porimin Primary Antibodies »

Product Specifications

Immunogen

This antibody was generated by immunizing rabbits with a synthetic peptide corresponding to amino acids 173-188 SRRGIRYRTIDEHDAI of human Porimin; GenBank no. AAG2164.1.

Reactivity Notes

Human, Mouse reactivity reported in scientific literature (PMID: 16814713).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Porimin Antibody

Western Blot: Porimin Antibody [NB100-56371]

Western Blot: Porimin Antibody [NB100-56371]

Western Blot: Porimin Antibody [NB100-56371] - Analysis of Porimin using NB100-56371 at 2 ug/ml dilution against 20 ug/lane of HL60 cell lysate.

Applications for Porimin Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:10-1:500. Use reported in scientific literature (PMID 16814713)

Western Blot

1-3 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Porimin

Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110-kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.

Long Name

Pro-Oncosis Receptor Inducing Membrane Injury

Alternate Names

KCT3, TMEM123

Entrez Gene IDs

114908 (Human); 71929 (Mouse); 363013 (Rat)

Gene Symbol

TMEM123

UniProt

Q8N131 (Human)

Additional Porimin Products

Product Documents for Porimin Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Porimin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Porimin Antibody

Customer Reviews for Porimin Antibody

There are currently no reviews for this product. Be the first to review Porimin Antibody and earn rewards!

Have you used Porimin Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies