PR 619

Catalog # Availability Size / Price Qty
4482/10
4482/50
Deubiquitinating Enzyme Inhibitors Small Molecule
1 Image
Description: Broad spectrum DUB inhibitor

Chemical Name: 2,6-Diamino-3,5-dithiocyanopyridine

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Broad spectrum, reversible DUB inhibitor. Exhibits limited activity against other proteases. Induces accumulation of polyubiquitinated proteins, but has no direct inhibitory effect on the proteasome. Cytotoxic in HEK293T and colorectal cancer cells. Stabilizes microtubule network in oligodendroglial cells.

Technical Data

M.Wt:
223.28
Formula:
C7H5N5S2
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2645-32-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for PR 619

The citations listed below are publications that use Tocris products. Selected citations for PR 619 include:

1 Citation: Showing 1 - 1

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for PR 619

There are currently no reviews for this product. Be the first to review PR 619 and earn rewards!

Have you used PR 619?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.