Pravastatin sodium salt

  ( 2 citations )    
Product Datasheet
Catalog Number:2318
Alternate Names:Eptastatin sodium
Chemical Name:(βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt
Product Details
Citations (2)
Reviews
Biological Activity
Water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties.
Technical Data
  • M.Wt:
    446.51
  • Formula:
    C23H35NaO7
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Desiccate at RT
  • CAS No:
    81131-70-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Pravastatin sodium salt include:

2 Citations: Showing 1 - 2
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  1. AMP-Activated Protein Kinase Alpha 2 Deletion Induces VSMC Phenotypic Switching and Reduces Features of Atherosclerotic Plaque Stability.
    Authors: Ding Et al.
    Circ Res  2016;119:718
  2. Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.
    Authors: Vainio Et al.
    Proc Natl Acad Sci U S A  2011;2:1176

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