Recombinant Human PRL-3/PTP4A3 His Protein

Name: Recombinant Human PRL-3/PTP4A3 His Protein
Brand: Novus Biologicals
SKU: NBP1-30246
Price: 299 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-30246

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all PRL-3/PTP4A3 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-173 of Human PRL-3/PTP4A3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MARMNRPAPV EVSYKHMRFL ITHNPTNATL STFIEDLKKY GATTVVRVCE VTYDKTPLEK DGITVVDWPF DDGAPPPGKV VEDWLSLVKA KFCEAPGSCV AVHCVAGLGR APVLVALALI ESGMKYEDAI QFIRQKRRGA INSKQLTYLE KYRPKQRLRF KDPHTHKTRC CVM

Purity

>95%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Predicted Molecular Mass

21.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PRL-3/PTP4A3 His Protein

SDS-PAGE: Recombinant Human PRL-3/PTP4A3 His Protein [NBP1-30246]

SDS-Page: Recombinant Human PRL-3/PTP4A3 Protein [NBP1-30246] - PRL-3, 21.6 kDa (193aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Formulation, Preparation, and Storage

NBP1-30246

Formulation	20 mM Tris-HCl buffer (pH8.0), 2 mM EDTA, 1 mM DTT, 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRL-3/PTP4A3

Protein tyrosine phosphatase type IVA 3 (PRL-3), as known as PTP4A3, belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) that remove phosphate modifications from tyrosine residues on proteins. This protein enhances cell proliferation, cell motility and invasive activity. High levels of PRL-3 expression are associated with tumorigenesis and metastasis, thus it is overexpressed in metastatic colorectal, ovarian, liver and skin cancers. Recombinant human PRL-3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Long Name

Phosphatase of Regenerating Liver 3

Alternate Names

PRL3, PTP4A3

Gene Symbol

PTP4A3

Additional PRL-3/PTP4A3 Products

Product Documents for Recombinant Human PRL-3/PTP4A3 His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human PRL-3/PTP4A3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Phosphatases and Regulators

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