Key Product Details

Species Reactivity

Human

Applications

Radioimmunoassay

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 11P14

Format

BSA Free
View all Progesterone Primary Antibodies »

Product Specifications

Immunogen

11a-Hydroxyprogesterone conjugated to bovine serum albumin.

Localization

Secreted

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Progesterone Antibody (11P14) - BSA Free

Application
Recommended Usage

Radioimmunoassay

1:100 - 1:2000
Application Notes
11P14 can be used for detecting and measuring progesterone levels in serum and tissue.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Progesterone

Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Progesterone receptor, a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone. The PGR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. Although PRA and PRB share several structural domains, they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap. It is composed of three domains: a modulating N terminal domain, a DNA binding domain and a C terminal steroid binding domain. Progesterone levels 1. men 30-60 pg/0.1ml 2. women pre ovulatory phase: 20-160 pg/0.1ml; ovulatory phase: 1,000-1,700 pg/0.1ml; post ovulatory phase: 1,000-1,700 pg/0.1ml; Pregnant: 16-18 weeks: 300-800 pg/0.1ml; 28-30 weeks: 6,500-14,700 pg/0.1ml; 38-40 weeks: 12,000-19,000 pg/0.1ml.

Alternate Names

4-Pregnen-3,20-dione

Additional Progesterone Products

Product Documents for Progesterone Antibody (11P14) - BSA Free

Certificate of Analysis

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Product Specific Notices for Progesterone Antibody (11P14) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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