Biological Activity DYRK1A/B inhibitor; prodrug form of INDY (Cat. No. 4997). Cell permeable. Inhibits phosphorylation of tau protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo.
Soluble to 100 mM in DMSO
Store at -20°C
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