ProINDY

Catalog # Availability Size / Price Qty
4998/10
Cat.No. 4998 - ProINDY | C14H15NO3S | CAS No. 719277-30-2
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Description: DYRK1A/B inhibitor; prodrug of INDY (Cat. No. 4997)

Chemical Name: (1Z)-1-(5-Acetyloxy3-ethyl-2(3H)-benzothiazolylidene)-2-propanone

Product Details
Citations (2)
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Biological Activity

DYRK1A/B inhibitor; prodrug form of INDY (Cat. No. 4997). Cell permeable. Inhibits phosphorylation of tau protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo.

Technical Data

Formula:
C14H15NO3S
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
719277-30-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citations for ProINDY

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