DYRK1A/B inhibitor; prodrug form of INDY
(Cat. No. 4997). Cell permeable. Inhibits phosphorylation of tau protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus
embryos from head malformation induced by DYRK1A overexpression in vivo
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All Tocris products are intended for laboratory research use only.
Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.
Ogawa et al.
The citations listed below are publications that use Tocris products. Selected citations for ProINDY include:
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