ProINDY

Catalog # Availability Size / Price Qty
4998/10
DYRK Inhibitors Small Molecule
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Description: DYRK1A/B inhibitor; prodrug of INDY (Cat. No. 4997)

Chemical Name: (1Z)-1-(5-Acetyloxy3-ethyl-2(3H)-benzothiazolylidene)-2-propanone

Purity: ≥98%

Product Details
Citations (2)
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Biological Activity

DYRK1A/B inhibitor; prodrug form of INDY (Cat. No. 4997). Cell permeable. Inhibits phosphorylation of tau protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo.

Technical Data

M.Wt:
277.34
Formula:
C14H15NO3S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
719277-30-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for ProINDY

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