PSB 12379

Catalog # Availability Size / Price Qty
6083/10
PSB 12379 | Other ATPase Inhibitors
1 Image
Description: Ecto-5'-nucleotidase (CD73) inhibitor

Chemical Name: N6-Benzyl-α,β-methyleneadenosine 5'-diphosphate disodium salt

Purity: ≥98%

Product Details
Reviews

Biological Activity

PSB 12379 is a selective high affinity ecto-5'-nucleotidase/CD73 inhibitor (Ki values are 2.21 and 9.03 nM at human and rat CD73, respectively). Blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. Exhibits selectivity over other ecto-nucleotidases and ADP-activated P2Y receptors tested.

Technical Data

M.Wt:
559.31
Formula:
C18H21N5Na2O9P2
Solubility:
Soluble in water (supplied pre-dissolved at a concentration of 10mM)
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Complete Your Research

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for PSB 12379

There are currently no reviews for this product. Be the first to review PSB 12379 and earn rewards!

Have you used PSB 12379?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.