Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG1 Clone # 764209
View all PTP pi/PTPRU Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human PTPπ/PTPRU
Glu19-Gln740
Accession # Q92729

Specificity

Detects human and rat PTPπ/PTPRU in Western blots and recombinant human PTPRU in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) PTPRK, rhPTPRM, or rhPTPRT is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for PTP pi/PTPRU Antibody (764209) [Biotin]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PTP pi/PTPRU

The protein encoded by the PTPRU gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Three alternatively spliced transcript variants, which encode distinct proteins, have been reported. (provided by RefSeq)

Long Name

Receptor-type Protein Tyrosine Phosphatase pi

Alternate Names

FMI, GLEPP1, PCP-2, pi R-PTP-Psi, PTP-J, PTP-PI, PTPRO, PTPRU, R-PTP-U

Gene Symbol

PTPRU

Additional PTP pi/PTPRU Products

Product Documents for PTP pi/PTPRU Antibody (764209) [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for PTP pi/PTPRU Antibody (764209) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Epigenetics
Phosphatases and Regulators

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