Pyrrolidinedithiocarbamate ammonium

Catalog # Availability Size / Price Qty
0727/50
Pyrrolidinedithiocarbamate ammonium | CAS No. 5108-96-3 | NFkB/IkB Inhibitors
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Description: Inhibits NF-κB, prevents increase in NOS mRNA
Alternative Names: PDTC
Product Details
Citations (8)
Reviews (1)

Biological Activity

This inhibitor of nuclear factor κB (NF-κB) prevents the increase in NO-synthase mRNA by interleukin-1, without affecting the formation of NO-synthase mRNA produced by cAMP.

Technical Data

M.Wt:
164.28
Formula:
C5H12N2S2
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at RT
CAS No:
5108-96-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Pyrrolidinedithiocarbamate ammonium

The citations listed below are publications that use Tocris products. Selected citations for Pyrrolidinedithiocarbamate ammonium include:

8 Citations: Showing 1 - 8

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PDTC inhibits HOCl-LDL-induced CaMKII oxidation
By Chintan Koyani on 10/22/2018
Application: Species: Mouse

HL-1 cardiomyocytes were pre-treated with Pyrrolidinedithiocarbamate (PDTC, 1 mM), Tempol (1 mM) or N-Acetylcysteine (NAC, 1 mM) for 30 min and stimulated with HOCl-LDL (200 µg/ml) for 2 h to follow CaMKII oxidation using Western blot.


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