This inhibitor of nuclear factor κ
B) prevents the increase in NO-synthase mRNA by interleukin-1, without affecting the formation of NO-synthase mRNA produced by cAMP.
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Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor κB (NF-κB) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes.
Bessho et al.
Pyrrolidine dithiocarbamate differentially affects 1β- and cAMP-induced NO-synthase expression in rat renal mesangial cells.
Eberhardt et al.
Pyrrolidine dithiocarbamate selectively prevents the expression of the inducible nitric oxide synthase in the rat aorta.
The citations listed below are publications that use Tocris products. Selected citations for Pyrrolidinedithiocarbamate ammonium include:
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