GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β
-catenin signaling pathway to upregulate β
-catenin nuclear translocation. Also reduces in vitro
migration of metastatic human breast cancer cells.
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All Tocris products are intended for laboratory research use only.
Small-molecule synergist of the Wnt/β-catenin signaling pathway.
Zhang et al.
A chemical approach to stem cell biology
Emre et al.
The citations listed below are publications that use Tocris products. Selected citations for QS 11 include:
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