Quin C1

Key Product Details

Product Description

Quin C1 is a potent and selective FPR2 agonist (EC₅₀ = 15 nM). Induces Ca²⁺ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model. Anti-inflammatory.

Product Specifications for Quin C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Quin C1

The following data is based on the product molecular weight 445.51.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.24 mL	11.22 mL	22.45 mL
5 mM	0.45 mL	2.24 mL	4.49 mL
10 mM	0.22 mL	1.12 mL	2.24 mL
50 mM	0.04 mL	0.22 mL	0.45 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

• Corminboeuf FPR2/ALXR agonists and the resolution of inflammation. J.Med.Chem. 2014 PMID: 25365541
• Zhou Pharmacological characterization of a novel nonpeptide antagonist for formyl peptide receptor-like 1. Mol.Pharmacol. 2007 PMID: 17652444

Product Documents for Quin C1