Quin C1

Catalog # Availability Size / Price Qty
5583/10
5583/50
Cat.No. 5583 - Quin C1 | C26H27N3O4 | CAS No. 786706-21-6
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Description: Potent and selective FPR2 agonist

Chemical Name: 4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Potent and selective FPR2 agonist (EC50 = 40 nM). Induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model. Anti-inflammatory.

Technical Data

M.Wt:
445.51
Formula:
C26H27N3O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
786706-21-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for Quin C1

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