Potent and selective FPR2 agonist (EC50
= 40 nM). Induces Ca2+
mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro
. Reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model. Anti-inflammatory.
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Pharmacological characterization of a novel nonpeptide antagonist for formyl peptide receptor-like 1.
Zhou et al.
FPR2/ALXR agonists and the resolution of inflammation.
Corminboeuf et al.
The citations listed below are publications that use Tocris products. Selected citations for Quin C1 include:
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