Catalog Number: 1519
Alternate Names: LY 163502
Chemical Name: (5aR,9aR)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride
Biological Activity
Dopamine D2 and D3 receptor agonist; Ki values are 5.7 and 3.4 nM respectively.
Technical Data
  • M.Wt:
    319.27
  • Formula:
    C14H22N4.2HCl
  • Solubility:
    Soluble to 25 mM in water
  • Purity:
    >99%
  • Storage:
    Desiccate at RT
  • CAS No:
    97548-97-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Eli Lilly and Company
Background References
  1. Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic agonist.
    Foreman et al.
    J.Pharmacol.Exp.Ther., 1989;250:227
  2. Effects of the selective dopaminergic D2 agonist quinelorane on the activity of dopaminergic and noradrenergic neurons projecting to the diencephalon of the rat.
    Eaton et al.
    J.Pharmacol.Exp.Ther., 1994;268:645
  3. Comparison of D2 and D3 dopamine receptor affinity of dopaminergic compounds in the rat brain.
    Flietstra and Levant
    Life Sci., 1998;62:1825

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