Catalog Number: 0225
Chemical Name: Pyridine-2,3-dicarboxylic acid
Biological Activity
Endogenous NMDA agonist and transmitter candidate. May distinguish between NMDA receptor subtypes.
Technical Data
  • M.Wt:
    167.12
  • Formula:
    C7H5NO4
  • Solubility:
    Soluble to 50 mM in 1eq. NaOH
  • Storage:
    Store at RT
  • CAS No:
    89-00-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Quinolinate differentiates between forebrain and cerebellar NMDA receptors.
    Monaghan and Beaton
    Eur.J.Pharmacol., 1991;194:123
  2. The endogenous agonist quinolinic acid and the non-endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits.
    Prada de Carvalho et al.
    Neurochem.Int., 1996;28:445
  3. NMDA receptors and ligands in the vertebrate CNS.
    Stone and Burton
    Prog.Neurobiol., 1988;30:333
  4. Quinolinic acid: a potent endogenous excitant at amino acid receptors in the rat CNS.
    Stone and Perkins
    Eur.J.Pharmacol., 1981;72:411
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Quinolinic acid include:

1 Citations: Showing 1 - 1

  1. Milnacipran remediates impulsive deficits in rats with lesions of the ventromedial prefrontal cortex.
    Authors: Tsutsui-Kimura Et al.
    Nat Commun 2015;18

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