Quipazine dimaleate

Key Product Details

Product Description

Quipazine dimaleate is a selective 5-HT₃ receptor agonist. Also displays antagonist activity at peripheral 5-HT₃ receptors. [³H]-Quipazine labels 5-HT₃ sites in the cortical membranes.

Product Specifications for Quipazine dimaleate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Quipazine dimaleate

The following data is based on the product molecular weight 445.43.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.25 mL	11.23 mL	22.45 mL
5 mM	0.45 mL	2.25 mL	4.49 mL
10 mM	0.22 mL	1.12 mL	2.25 mL
50 mM	0.04 mL	0.22 mL	0.45 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

• Peroutka and Hamik [³H]Quipazine labels 5-HT₃ recognition sites in rat cortical membranes. Eur.J.Pharmacol. 1988 PMID: 3378579
• Sharif Characteristics of 5-HT₃ binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [³H]-quipazine and [³H]-GR65630 binding. Br.J.Pharmacol. 1991 PMID: 1830236
• Ireland and Tyers Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br.J.Pharmacol. 1987 PMID: 3814920

Product Documents for Quipazine dimaleate