Catalog Number: 1043
Chemical Name: 2-[(2,6-Dimethylphenyl)amino]-N,N,N-trimethyl-2-oxoethaniminium chloride
Biological Activity
Sodium channel blocker.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Local anaesthetic blockade of neuronal nicotinic ACh receptor-channels in rat parasympathetic ganglion cells.
    Cuevas and Adams
    Br.J.Pharmacol., 1994;11:663
  2. Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study.
    Hanck et al.
    J.Gen.Physiol., 1994;103:19

The citations listed below are publications that use Tocris products. Selected citations for QX 222 include:

Showing Results 1 - 2 of 2

  1. Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin.
    Authors: Li Et al.
    Antimicrob Agents Chemother
  2. Ion selectivity filter regulates local anesthetic inhibition of G-protein-gated inwardly rectifying K+ channels.
    Authors: Slesinger
    Biophys J
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