(R)-2-Hydroxyglutaric acid disodium salt

Product Datasheet
Catalog Number:6124
Alternate Names:D-α-hydroxyglutaric acid disodium salt
Chemical Name:(R)-2-Hydroxypentanedioic acid disodium salt
Product Details
Biological Activity
Oncometabolite produced by mutant isocitrate dehydrogenase 1 (IDH1) and IDH2. Inhibits KDM4A in murine embryonic fibroblasts resulting in activation of mTOR. Also activates NF-κB in bone marrow stromal cells.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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