Catalog Number: 1395
Chemical Name: (R)-3,4-Dicarboxyphenylglycine
Biological Activity
AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors.

Racemate and S-enantiomer also available.

Technical Data
  • M.Wt:
    239.18
  • Formula:
    C10H9NO6
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >96%
  • Storage:
    Desiccate at RT
  • CAS No:
    201730-10-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice.
    Moldrich et al.
    Neuropharmacology, 2001;40:732
  2. Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones.
    Thomas et al.
    Eur.J.Pharmacol., 1997;338:111
Citations:

The citations listed below are publications that use Tocris products. Selected citations for (R)-3,4-DCPG include:

1 Citations: Showing 1 - 1

  1. Structure based model for the prediction of phospholipidosis induction potential of small molecules.
    Authors: Sun Et al.
    J Chem Inf Model 2012;52:1798
Tocris Small Molecules
Description Application Cat# Citations Images  

(RS)-3,4-DCPG

1394  
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