R 715

Tocris Bioscience | Catalog # 3407

Potent and selective B1 antagonist
Tocris Bioscience
Discontinued Product
3407 has been discontinued. View all Bradykinin Receptor Antagonists products.

Key Product Details

Description

Potent and selective B1 antagonist
View all Bradykinin Receptor Antagonists »

Product Description

R 715 is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Metabolically stable.

Product Specifications for R 715

Molecular Weight

1140.35

Formula

C57H81N13O12

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

185052-09-9

PubChem ID

5311397

InChI Key

DOSXOGUJJBDRGQ-VUBDHFCFSA-N

SMILES

CC[C@H](C)[C@H](NC(=O)[C@@H](CC1=CC2=CC=CC=C2C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(C)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 5mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 30 publications citing the usage of this product.

Product Documents for R 715

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for R 715

For research use only

Customer Reviews for R 715 (1)

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  • works good
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: neurons
    Verified Customer | Posted 05/13/2020
    treat 20 min
    B1 receptor antagonist R715, 2 µM
    R 715 3407

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