Catalog Number: 6033
Chemical Name: N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-D-leucinamide
Biological Activity
Potent 20S proteasome inhibitor (IC50 = 0.22 nM). Exhibits cytostatic and cytotoxic effects in tumor cells in vitro.
Technical Data
  • M.Wt:
    475.63
  • Formula:
    C26H41N3O5
  • Solubility:
    Soluble to 100 mM in DMSO and to 20 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    1211877-36-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Studies of the synthesis of all stereoisomers of MG-132 proteasome inhibitors in the tumor targeting approach.
    Mroczkiewicz et al.
    J.Med.Chem., 2010;53:1509
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