(R)-MG 132

Key Product Details

Product Description

(R)-MG 132 is a potent 20S proteasome inhibitor (IC₅₀ = 0.22 nM). Exhibits cytostatic and cytotoxic effects in tumor cells in vitro.

Product Specifications for (R)-MG 132

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for (R)-MG 132

The following data is based on the product molecular weight 475.63.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.10 mL	10.51 mL	21.02 mL
5 mM	0.42 mL	2.10 mL	4.20 mL
10 mM	0.21 mL	1.05 mL	2.10 mL
50 mM	0.04 mL	0.21 mL	0.42 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

• Mroczkiewicz Studies of the synthesis of all stereoisomers of MG-132 proteasome inhibitors in the tumor targeting approach. J.Med.Chem. 2010 PMID: 20112914

Product Documents for (R)-MG 132