(R)-(-)-Phenylephrine hydrochloride

Catalog # Availability Size / Price Qty
2838/100
(R)-(-)-Phenylephrine hydrochloride | CAS No. 61-76-7 | Adrenergic alpha-1 Receptor Agonists
2 Images
Description: α1 agonist

Chemical Name: (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride

Purity: ≥99%

Product Details
Citations (4)
Supplemental Products
Reviews

Biological Activity

(R)-(-)-Phenylephrine hydrochloride is a α1-adrenoceptor agonist; pKi values are 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively.

Scientific Data

Binding Activity phenylephrine affects cardiomyocyte contraction rates View Larger

Small molecules affect cardiomyocyte contraction rates. The effect of small molecules on cardiomyocyte contraction rate was assessed by monitoring intracellular calcium fluctuations, where an increase in calcium coincides with cardiomyocyte contraction. Cardiomyocytes were loaded with the fluorescent calcium indicator, Fluo-4, prior to small molecule treatment. Individual wells were first monitored for baseline rates of calcium fluctuation represented as beats per minute (bpm). Phenylephrine (3μM, Catalog # 2838), an alpha 1-adrenoceptor agonist, increased the calcium fluctuation rate of cardiomyocytes compared to untreated cells

Technical Data

M.Wt:
203.67
Formula:
C9H13NO2.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
61-76-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for (R)-(-)-Phenylephrine hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for (R)-(-)-Phenylephrine hydrochloride include:

4 Citations: Showing 1 - 4

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for (R)-(-)-Phenylephrine hydrochloride

There are currently no reviews for this product. Be the first to review (R)-(-)-Phenylephrine hydrochloride and earn rewards!

Have you used (R)-(-)-Phenylephrine hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.